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Hip Dysplasia
(HD) and Elbow Dysplasia (ED) assessments
are only required to be done once in an animal's life,
after the age of 12 months, and the results are applicable
to the life of the animal. (KUSA are in the process of
adopting the FCI HD grading system. The new regulations
will be applicable with effect from 1 January, 2007).
Dilated Cardiomyopathy (DCM): Heart
scan can be done but results are only valid at time of
scan. Try to find out as much as you can about the ancestors
- to what age did they live, what was the cause of death. One of the gene mutations that affects the heard in Dobermanns has now been idetified and can be tested for. It is at this stage not totally definitive but will enable a breeder to avoid breeding two known high risk dogs.
von Willebrand's Disease (vWD): The vWD test
is a DNA test, the result of which is applicable to the
life of the animal. See the following guidelines:
The following table clearly shows the risk in mating Carrier-to-Carrier
and Carrier-to-Affected and Affected-to-Affected:
| Breeding
Pair Combinations |
CLEAR MALE |
CARRIER MALE |
AFFECTED MALE |
| CLEAR FEMALE |
100% Clear |
50/50 Carrier/Clear |
100% Carrier |
| CARRIER FEMALE |
50/50 Carrier/Clear |
25/50/25 Clr./Carr./Affctd. |
50/50 Carrier/Affected |
| AFFECTED FEMALE |
100% Carrier |
50/50 Carrier/Affected |
100% Affected |
Ideal Breeding Pair: Clear to Clear. Puppies will not
have the disease gene (neither as Carrier nor as Affected).
Breeding Is Safe: Clear to Carrier. No Affected puppies
will be produced. However, some or all puppies will be
Carriers. Accordingly, it is recommended that Carrier dogs
which are desirable for breeding be bred with Clear dogs
in the future, which will produce 50% carrier and 50% clear
animals, to further reduce the disease gene frequency.
These offspring should be tested by VetGen's test for this
defective gene, and if possible, only the clear animals
in this generation should be used.
High Risk Breeding: Carrier to Carrier/Affected to Carrier. Some puppies are
likely to be Carriers and some puppies are likely to be
Affected. Even though it is possible that there will be
some clear puppies when breeding 'Carrier to Carrier',
in general, neither this type of breeding pair nor 'Carrier
to Affected' are recommended for breeding.
Breeding Not Recommended: Affected to Affected. All puppies
will be genetically Affected.
Eye Tests: Of the eye
problems currently tested for in SA PHTVL/PHPV is the most
significant. PHTVL/PHPV only needs to be tested once during
the dog's lifetime. If the dog is clear at the time of
the testing this will not change at a later stage.
Thyroid: Inheritability
is low. TSH and T4 tests can be done but results are only
valid at the time of testing. Testing available from your
usual vet if you feel your dog has symptoms indicating
a problem.
Auto Immune Deficiency Syndrome: No
information at present.
Cervical Vertebral Instability
(CVI, Wobblers): Hereditary degenerative disease
of the neck spinal column, occurring most commonly in
middle age (4 to 7). No test available but check on the
ancestors. Surgery is the only successful treatment.
Demodectic Mange: An
immune system problem assumed to be passed on from the
dam - in severe cases significant hair loss and extreme
itchiness. Only identifiable when condition occurs but
it can be very uncomfortable for the dog and expensive
to treat.
| Health
Test |
Test
Authority |
Country |
Type
of Test |
| HD / ED |
Onderstepoort (OP) |
SA |
X-Rays |
| |
Any veterinary practice, where
x-ray facilities are available, to be certified by
Dr Kirberger (OP) |
|
|
| PHTVL / PHPV |
Onderstepoort |
SA |
Examination by
vet |
| |
JHB Animal Eye Hospital |
|
|
| DCM |
Onderstepoort |
SA |
Echo cardiogram |
| |
Provinces |
|
Echo cardiogram |
| |
Veterinary Cardiac Genetics Laboratory, WSU |
USA |
DNA brushes/blood sample |
| vWD |
VetGen |
USA |
Saliva / Blood sample |
| |
Laboklin |
Germany |
|
| Thyroid (TSH
function + Total T4) |
Onderstepoort |
SA |
Blood sample |
| Herpes |
Onderstepoort |
SA |
Blood sample |
| CVI / Wobblers |
Onderstepoort |
SA |
Myelogram, MRI |
| |
Qualified specialists |
|
|
| Demodectic Mange |
Local vet |
SA |
Skin sample |
Veterinarians accepted to do Scans for DCM:
| Johannesburg: |
Dr. Gary Eckersley
Tel.: (011) 702-1957 |
| Cape Town: |
Cape Animal Medical Centre
Tel.: (021) 674-0034
Tygerberg Animal Hospital (lower cost option by special arrangement)
|
| Durban: |
Westville Animal Hospital
Dr. Winberley
Tel.: (031) 267-8020 |
| Port Elizabeth |
Kagga Kama Veterinary Clinic
Dr. Dave Euzared
Tel.: (041) 379-2740 |
| Dr. Euzared would be able
to receommend a vet in East London should
there be one in that area qualified to do Cardio
Scans. |
Veterinarians accepted to do Eye Tests:
| Johannesburg: |
Johannesburg Animal Eye Hospital
Drs. Venter & Goodhead
Tel.: (011) 465-1237 |
| Pretoria: |
Eye tests are performed at Onderstepoort on Monday
and Tuesday mornings, but bookings need to be made
through JHB Animal Eye Hospital.
Tel.:(011) 465-1237. |
| Cape Town: |
Panorama Veterinary Clinic.
Tel.:(021) 930 6632
|
| Durban: |
Drs. Venter and Goodhead consult at Westville Animal
Hospital every 4 - 5 months, so please phone to make
a booking and to ascertain when the above Drs. will
be consulting at this practice.
Tel.: (031) 267-8020 |
| Bloemfontein: |
Drs. Venter and Goodhead consult at Bayswater Animal
Hospital every 4 - 5 months, so please phone to make
a booking and to ascertain when the above Drs. will
be consulting at this practice.
Tel.: (051) 436-6604 |
| Nelspruit: |
Drs. Venter and Goodhead consult at West Acres
Animal Hospital every 4 - 5 months, so please phone
to make a booking and to ascertain when the above
Drs. will be consulting at this practice.
Tel.: (013) 741-2026 |
| There are at present no facilities
in Port Elizabeth or East
London for eye testing. |
von Willebrand's Disease testing can now be done in South Africa:
Inqaba Biotechnical Industries (Pty) Ltd
Cell: 082 859 2229
Tel: 012 343 5829 or 018 290 6926
Fax: 012 343 0287
or
| Germany: |
Laboklin - Laboratory for Clinical Diagnostics
Prinzregentenstrasse 3
97688 Bad Kissingen
Germany.
Tel.: 0949 971 72020
Fax: 0949 971 68546
Please note that Nikki Redtenbacher (083
651 1133) can be contacted for group
tests submitted to Laboklin on occasion. |
| United States of America: |
Vetgen - Veterinary Genetic Services
3728 Plaza Drive, Suite 1, Ann Arbor,
Michigan, 48108 USA
Tel.: 091 734 669-8440
Fax: 091 734 669-8441 |
Thyroid and Herpes test
can be done through your regular veterinarian as
it is only a blood sample which needs to be sent
to Onderstepoort for analysis.
CVI/Wobblers diagnosis can start
with your vet, but it is probable that specialist
help may be needed.
Demodectic Mange. Your own vet
should be able to take skin samples for analysis.
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